Primary hyperthyroidism can be completely cured by oral treatment with SAGE in some patients, while hyperthyroidism may be controlled for a short period of time after oral treatment with SAGE in other patients, but may recur after stopping the drug. The recurrence of hyperthyroidism is closely related to the level of thyroid hormones, goiter and serum level of thyrotropin receptor antibodies. Sage is currently the most effective drug in the treatment of primary hyperthyroidism, the main side effects may be damage to liver function, and may also lead to a decrease in white blood cells and neutrophils in the course of treatment, but these side effects can be treated with the appropriate medication.