Gallbladder inflammation does not necessarily mean gallstones, but more commonly gallstones combined with inflammation of the gallbladder, because after the stones have been inside the gallbladder for a long time, they can affect the mucosa of the gallbladder and may lead to chronic cholecystitis or acute cholecystitis. However, there are some patients with stone free cholecystitis, which means that the gallbladder itself has inflammation, such as edema and thickening of the gallbladder wall, oozing around the wall, and the patient has abdominal pain, but there are no stones inside the gallbladder during hepatobiliary ultrasonography. For cholecystitis without stones, surgery is recommended after a clear diagnosis because there may be other causes of gallbladder inflammation, such as high blood sugar and gallbladder vasculopathy, which lead to inflammation of the patient’s gallbladder, and usually the inflammation of the gallbladder is more severe and may lead to gallbladder gangrene and gallbladder perforation.