Long-term over-injection and frequent injections of wrinkle-reducing injections may result in facial stiffness. This is related to its principle of wrinkle reduction. The botulinum toxin, a biotoxic muscle relaxant, inhibits the release of acetylcholine and blocks neuromuscular transmission, resulting in relaxation paralysis of the muscles, thus inhibiting muscle contraction for the purpose of removing wrinkles. Long-term injection of wrinkle removal injections will cause the muscles to lose their effect, and it will present a condition of facial stiffness. In fact, for now, there are many ways to remove wrinkles, there is no need to keep on loving wrinkle removal injections. To remove wrinkles, there are many methods available to you besides Botox, like hyaluronic acid and autologous fat filler, which are more familiar to everyone. If there are not only wrinkles but also facial laxity and sagging, you can choose thread sculpture and five-layer face lift. Of course, which option is suitable for you depends on the degree of your facial aging. Different parts of the aging, the appropriate method also differs, the following targeted for you to talk about. We can use hyaluronic acid and autologous fat filler to solve these wrinkles, such as head lines, frown lines, crow’s feet and decree lines. Although, hyaluronic acid will not make the face stiff, but it needs to be injected frequently, because hyaluronic acid maintenance time is about 6 months. If you want to keep permanent effect, it is recommended to use autologous fat filler. Problems like chin curve lifting, side face curve modification, and overall facial rejuvenation can only be solved by such methods as thread sculpting and facial minimally invasive. In addition, for candidates over 35 years old with severe skin laxity and sagging, thread sculpting is a simple lifting of the superficial skin layer, which is more suitable for face lift surgery to improve.