The symptoms that may appear in the early stage of chronic kidney disease can serve as a warning for the occurrence of chronic kidney disease, facilitating the early diagnosis and treatment of chronic kidney disease patients and effectively curbing the deterioration of the disease. Usually, when there is a large amount of foam in the urine, blood color seen in the urine, increased nocturia, swelling of both lower limbs or both eyes, i.e., urine protein and red blood cells appear in the urine of routine urine examination, it may be an early warning sign of the early occurrence of chronic kidney disease. Usually patients with chronic nephritis do not have particularly obvious symptoms of discomfort. Therefore, it is recommended to seek medical examination and diagnosis when there is abnormal urine. Once patients feel that they have obvious fatigue, anemia and other very obvious symptoms before they go to the doctor, the chronic kidney disease may have passed the early stage, which will bring greater difficulty in the late treatment of chronic kidney disease.