Trimethoprim cream can be used in infants if they have limited eczema or dermatitis. However, if the infant has large patches of eczema or large patches of oozing, Trimethoprim Cream should not be used over a large area. If the child or infant has large patches of eczema or even oozing, non-hormonal medications must be applied externally, such as cold compresses with saline or 3% boric acid solution. You can also use traditional Chinese medicine, such as amaranth decoction, and then cold compresses, or use proprietary Chinese medicines, such as children’s skin Kang lotion to cold boiled water and then cold compresses.