The patient, male, 47 years old, complained of back pain and weakness for more than 2 months and was diagnosed with liver metastasis of pancreatic cancer for 20 days. History: The patient was admitted to the local hospital on March 26, 2015, and the CT scan of the abdomen suggested that the pancreas was occupying, with a size of about 6.0*4.1 cm, which was considered malignant, and multiple low-density foci in the liver with poorly defined borders, which was considered metastatic cancer. The retroperitoneum showed significantly enlarged lymph nodes, and metastasis was considered. On April 4, 2015, he was seen at 301 Hospital, and the swelling standard was checked: CA199:17102u/mol/L. The abdominal CT enhancement examination results showed that the tail of the pancreatic body was occupied, the size was about 6,5*5,7cm, the arterial phase was mildly enhanced, and the lesion was wrapped around the abdominal trunk and The lesion wrapped around the superior mesenteric artery and superior mesenteric vein. The lesion wrapped around the celiac trunk and superior mesenteric artery. Multiple low-density nodular masses in the liver, the larger one was about 6.7 cm in diameter, with mild circumferential enhancement in the arteriovenous phase and continuous circumferential enhancement in the portal vein and balance phase. The patient was admitted to our department for further diagnosis and treatment. He had the following symptoms: low back pain of grade 4, mainly on the right side, poor food intake, fatigue, loose stools, 1-2 times/day, poor night sleep, nocturnal urination twice, irritability and dry mouth, and weight loss of 10 kg in the past month. Past history: history of poliomyelitis, muscle atrophy of the right lower limb, and walking with a cane. History of hypertension for 5 years, highest blood pressure 160/100mmHg, oral Irbesartan 150mg, qd, Betalactam 25mg bid, blood pressure basically reached the standard. History of diabetes mellitus for 3 weeks, using Novolin 30R subcutaneous injection in the morning and evening, no blood glucose monitoring. History of sleep apnea syndrome, had performed minimally invasive treatment. Examination: T:35,8℃, P 86 times/min, BP 128/85mmHg, R 20 times/min, KPS 70 points, wheelchair pushed in, normal development, moderate nutrition, clear consciousness, cooperative examination, and tangential answers. There was no yellowing of the skin and mucous membranes, and no superficial lymph nodes were palpated throughout the body. There was no cranial deformity, both pupils were equally large and round, and he was responsive to light. The lips and mouth were not cyanotic, the tongue was stretched out in the center, and the pharynx was not red or swollen. The neck was soft, the trachea was in the center, and the thyroid gland was not large. The thorax was symmetrical, the breath sounds of both lungs were clear, and no obvious dry and wet rales were heard. The heart rate was 86 beats per minute, rhythmical, and no pathological murmur was heard in each valve. The abdomen was bulging, no mass was found, the liver and spleen were not enlarged and painful, mobile turbid sounds (-), normal bowel sounds, no percussion pain in the kidney area, muscle atrophy of the right lower limb, no deformity of the spine, normal physiological reflexes existed, pathological reflexes were not elicited. The tongue is dark red with thin coating and cracks. TCM diagnosis: internal cancer, spleen and kidney deficiency, phlegm and stagnation. Western medical diagnosis: 1, pancreatic malignancy (T4N1M1 stage IV) secondary malignant tumor of liver, secondary malignant tumor of retroperitoneal lymph nodes, secondary malignant tumor of bone (right 8th rib), pathological fracture. 2, hypertension grade 2 3, type 2 diabetes Patients refused surgery and chemotherapy. Integrative Chinese medicine treatment: static dosing of Kanglaite injection for anti-tumor, external application of Si Miao San acupressure, foot bath of No. 2 formula, oral tonics to tonify the kidney and strengthen the spleen, dispel blood stasis and resolve phlegm mainly, specific prescriptions are as follows. The formula is as follows: roasted astragalus 30, princely ginseng 30, poria 15, zhebei 10, tulip mother 10, ginger hemia 10, snake six gu 30 stretching grass 15, stone see through 15, jiao sanxian 30, half branch lotus 30, millennium Jian 10, earth turtle worm 10, yuan hu 10, neijin 10, white atractylodes 10. one dose daily, decoction with water. Blood count: WBC decreased from 16,6*10^9/L to 12,4*10^9/L. After discharge, the Chinese medicine prescription continued to be adjusted in the outpatient clinic, and there was no significant progress of swelling and lesions.