The time for the drug to work varies according to the physical condition of each person. The main ingredients of Ma Ren Rou Rou Wan are fire hemp seed, bitter almond, rhubarb and Chen Pi. Not all patients with constipation can use Ma Ren Run Yin Wan in clinical practice. The drug is mainly used to treat constipation with heat in the stomach and intestines. After the correct use of the drug, the effect is generally fast within a few hours, but if the constipation is more serious, the effect may be prolonged, taking about 1-3 days. It should be noted that constipation is mostly seen in the elderly, especially in female patients. It is mostly related to less eating, less activity, less secretion of digestive juices, weakening of intestinal peristaltic ability, prolonged stay of food residues in the intestine and repeated absorption of water. Of course, it is also related to too fine diet and bad bowel habits. In addition, some lesions of the intestine, such as tumors and hernias, which cause partial or complete intestinal obstruction, laxative abuse, and systemic diseases such as uremia, diabetes, and Parkinson’s disease, can also cause constipation. Therefore, patients with constipation are not recommended to self-medicate, and should be seen in a regular hospital to improve the relevant auxiliary examinations and exclude organic lesions. Adhere to physical exercise, cultivate good bowel habits, reasonable diet, mainly light and easy to digest food, and drink more water, ensure sufficient sleep, etc., are conducive to the prevention and treatment of constipation.