Uremia is an abnormal increase in urine output, usually caused by a decrease in antidiuretic hormone secreted by the pituitary gland or an insensitivity of the kidneys to antidiuretic hormone leading to a large increase in urine output. Uremia can be categorized into primary and secondary according to its etiology. Primary is due to pituitary dysfunction and treatment requires antidiuretic hormone supplementation, which is effective. Secondary refers to other causes of pituitary and hypothalamic lesions, such as pituitary tumors, trauma, etc., through the treatment of the primary disease can also be restored. Therefore, uremia is treatable and well treated, and is not a terminal disease.