The treatment of IgA nephrotic syndrome should be combined with treatment guidelines to control blood pressure to fully achieve the target and also take into account the level of 24h urine protein. In addition to the use of renin-angiotensin-aldosterone receptor antagonists, such as valsartan, irbesartan or captopril and lortensin, if the urine protein quantification is greater than 3.5 grams and nephrotic syndrome is present, this condition needs to be treated with a combination of adequate glucocorticoids. If thylakoid hyperplasia and 24h urine protein quantification is greater than 1 gram, it is also necessary to go through a full dose of glucocorticosteroid treatment. In case of podocytic hyperplasia and cellular crescent formation, but the number is less than 25% of all glomeruli, it is also possible to combine adequate hormone therapy with adequate RAS. In the absence of significant thylakoid hyperplasia, only intensive treatment with renin-angiotensin-aldosterone receptor antagonists is required.