Pulmonary adenocarcinoma infiltrating the pleura is advanced and very serious, which will cause pleural effusion chest. When the amount of pleural effusion is small, the patient will not experience significant discomfort as a result. When there is a large amount of pleural effusion, the lung tissue on the side of the pleural effusion is squeezed, causing pulmonary atelectasis, and the mediastinum and heart are pushed to the other side of the chest cavity by the pleural effusion, and the patient will experience chest tightness, shortness of breath, coughing, etc. In severe cases, the patient’s mobility can be significantly limited. The simplest way is to use a puncture needle to penetrate the chest cavity to extract the fluid to relieve the pressure on the chest cavity or to place a thin drainage tube to drain the chest fluid. If patients with lung cancer accompanied by pleural effusion are treated with intrathoracic local treatment, it is the symptom of the disease, while chemotherapy is administered to the patient’s primary tumor at the same time or after the intrathoracic local treatment, which can effectively eliminate the source of this type of pleural effusion.