Aminotransferases are enzymes that catalyze the transfer of amino acids to keto acids in the body. Aminotransferases exist in liver cells, and elevated aminotransferases are a sensitive indicator of liver cell damage. High aminotransferases are common in patients with liver injury, but they can also occur under certain physiological conditions, and are commonly found in the following situations: 1) exercise and exertion: after strenuous exercise or when working too hard, it may lead to high aminotransferases, which can be relieved by rest; 2) improper diet: inadequate nutrition, unreasonable diet structure, lack of cystine, vitamin E, or eating greasy food before the test The side effects of daily use of azithromycin, clarithromycin, antipyretic and analgesic drugs, antidepressants, antitumor drugs and some Chinese herbal medicines can lead to high transaminases, which need to be discontinued or replaced after communicating with doctors; 4. Hepatitis is the most common cause of high aminotransferases, which generally requires the application of anti-inflammatory and liver-protective drugs in combination with the cause, or the addition of antiviral drugs on top of anti-inflammatory and liver-protective treatment, noting that antiviral treatment needs to ensure the course of treatment and should not be stopped without authorization. In addition, autoimmune liver disease is also a common cause of high aminotransferases, which needs to be combined with specific types and given targeted treatment. Various chronic liver damage that develops into cirrhosis or even liver cancer can also result in high transaminases, requiring medication, surgery or even liver transplantation. 5. Biliary tract diseases: Acute attacks of cholecystitis and cholelithiasis can also cause high transaminases in addition to fever, abdominal pain, nausea, vomiting and jaundice. Bile duct obstruction caused by bile duct stenosis, stones and tumors can also cause high transaminases, which usually requires surgery.