Minimally invasive plastic surgery is the application of current advanced equipment and technology and aesthetic beauty concepts, including endoscopic technology, new materials and advances in injection technology, instead of traditional surgical methods, striving to complete fine surgical operations with tiny incisions and minimal tissue damage, with the remarkable features of less bleeding, light postoperative pain, quick recovery, short or no hospitalization, and inconspicuous or no scarring. So, what are the common drugs used in minimally invasive plastic surgery (injection plastic surgery)? The following introduces minimally invasive plastic surgery (injection plastic surgery) commonly used drugs: a, hyaluronic acid (hyaluronic acid) Hyaluronic acid is a hyaluronic acid (HYALURONICACID, abbreviated as HA), also known as glyoxylic acid. It has an average molecular weight between 100,000 and 10 million Dalton and is found in the intercellular matrix. Originally used only for moisturizing, it is now included in the ranks of plastic surgery. This plastic surgery technique uses non-animal stable hyaluronic acid cultivated by bacterial fermentation, and hyaluronic acid is injected into the dermis in the form of filler into the wrinkles and depressions, or the parts that wish to be plumped up, to achieve the effect of wrinkle removal and face modification, which can immediately remove wrinkles and change the appearance. Hyaluronic acid, which exists in the dermis of human skin in gel form, is responsible for storing water and increasing the volume of the skin, making the skin look full, plump and elastic. However, hyaluronic acid disappears with age, causing the skin to lose its ability to store water, gradually becoming dull, aging, and forming small wrinkles. Thanks to the advancement of biotechnology, hyaluronic acid can be extracted from the connective tissues of vertebrate animals, such as corns, eyeballs, umbilical cords, cartilage, and other parts. In the past, hyaluronic acid was mostly extracted from animals, but now it is synthesized artificially, eliminating problems such as allergies and infections. Hyaluronic acid indications: As an injectable filling material, hyaluronic acid has the widest range of indications and can be used to eliminate static lines on the face (including fine lines under the eyes; tail lines; tear troughs; bags under the eyes; decency lines, etc.), modify the shape of the lips, chin augmentation, nose transformation, cheek augmentation, fill hollows, etc. The advantages of hyaluronic acid injection: 1, very few side effects, the reason: a, hyaluronic acid is one of the components inherent in the human dermis, short residence time in the body, can be completely broken down by the body, there will be no long-term side effects b, not protein, allergic reactions are extremely rare. 2.It can be used for attempted lip augmentation, chin trimming, nose transformation, etc. 3.Fill evenly, there will be no prism or granular material left. 4.Simple and safe, fast and effective: no incision, only intra-dermal injection, avoiding the risk of surgery, and the curative effect is immediate. 5, natural ingredients: from biological tissue, so there is no foreign body feeling and foreign substances remain. 6.Comfortable and painless: there is only a slight local swelling and pain during the injection process, which is easy to accept. 7.Economic: the cost of minimally invasive cosmetic surgery is between life beauty and plastic surgery, and the price is relatively cheap. Hyaluronic acid side effects: temporary slight redness, swelling and itching may occur after hyaluronic acid injection, which usually disappears after a few days. Sometimes just after the injection, the skin will feel like a grainy stuff (invisible to the naked eye), which will disappear after about 3 days. Precautions for hyaluronic acid injection: 1. Avoid touching the injection area within 24 hours after the injection in order to make the shape fixed. 2.Appropriate ice packs can be applied before the injection, which will help to reduce the pain during the injection and at the same time reduce the swelling after the injection. 3.After injection, avoid strenuous exercise for a short period of time. 4.After the injection, maintain the general basic maintenance procedures and do not massage the treatment area in particular. 5.After the injection, avoid sauna for one week. 6.A week after injection, try to avoid taking aspirin or other similar blood-activating drugs. 7.A week after lip augmentation, try not to touch your lips when you eat, to avoid the loss of hyaluronic acid accelerated by eating too cold or too hot food. Second, French Iveran (Evolution}Outline) is a new generation of non-animal filling material that passed CE certification in 2000. It is divided into two categories. EVOLUTION is a long-lasting synthetic dermal filler, consisting of permeable spheres attached to a non-absorbable viscoelastic hydrogel. The specific ingredients are polyvinylidene microspheres, polyethylene cationic polymer, phosphate buffer, and water for injection. It does not contain any ingredients of animal origin and has no organic organism components of genetically modified origin. It is suitable for filling deep wrinkles and folds, lip augmentation, improving facial contours, and filling depressed scars. OUTLINE, on the other hand, does not come with a microsphere structure. It is a complete line of absorbable fillers for various wrinkles, including three products: FINE for shallow wrinkles and superficial epidermal folds, with a half-life of 1 year. ORIGINAL for shallow wrinkles, micro wrinkles and folds, lip augmentation, with a half-life of 2 years. ULTRA for deep wrinkles, micro wrinkles and folds, with a half-life of 5 years for facial contouring. Their mode of action works by replacing the extracellular matrix: the slowly absorbing polypropylene cationic polymer hydrogel acts as a filter to rearrange the leukocytes at the periphery of the implant while promoting the entry of soluble extracellular molecules (collagen, elastin, mucopolysaccharides, fibers, etc.). These molecules present in the extracellular environment with a negative charge are attracted by the force of the mild positive charge in EVOLUTION and OUTLINE, and in EVOLUTION these molecules come together to form microfibrils permeating the pores of the microspheres connected to form a stable 3-layer network structure. This process is a controlled physical process, not a physiological one, and the implant will remain stable and maintain approximately 65% of its initial volume. Composed entirely of synthetic substances, they do not contain potentially immunogenic substances, do not require allergy testing prior to injection, and can be stored at room temperature for direct use. All treatments typically have initial swelling, which generally subsides within a few hours. In rare cases, swelling can last all day. Bruising: Injections in the top layer of skin (fine wrinkles) rarely cause bruising, but deeper injections may cause it. By using a Vc mask immediately after treatment, bruising and swelling can be stopped. OUTLINE is CE certified and not recognized by the FDA. Third, Abeleve Artecoll This preparation has been approved by the US FDA and is a preparation of polymethylmethacrylate (PMMA), 30-40mm diameter small particles suspended in 1:3 bovine collagen containing 0,3% lidocaine. This microsphere is weakly immunogenic, has a smooth surface and was used in dental prostheses for many years. After injection, the bovine collagen gradually decomposes and the PMMA pellet is wrapped by human collagen within 3 months without obvious foreign body reaction and does not move in the body, and its effect is longer lasting. It has been twenty-two years since its invention in 1985, and eighteen years since it was first used in Germany in 1989, and has been clinically validated by the EU for seven years and the FDA for five years. After injection, apply moderate local pressure and gently massage the injection area within 3-5 days. Generally, the injection should be repeated 2-3 times to obtain long-term results. Complications: early swelling, sensitivity, bruising, allergic reactions similar to Zyderm and Zyplast, later, because the product can stimulate fibroplasia, may cause the occurrence of granulomas, its incidence is about 1/10,000. as more viscous, can be injected with a 27 needle, to inject the deeper layer of the skin. If the injection is too shallow, the area will be white and thick to the touch. There is also Resoplast, a bovine monomolecular collagen solution with concentrations of 3, 5%, 6, 5%, which is essentially Artecoll without PMMA. The U.S. FDA has not approved. Fourth, collagen collagen (collagen) exists in all multicellular animals, is the body’s most abundant class of proteins, exists in almost all tissues, is an extracellular protein, in the form of insoluble fibers, with a high degree of tensile capacity, is the main factor in determining the toughness of connective tissue. Collagen is a macromolecular protein, and the filamentous collagen fibers keep the skin firm and elastic. Collagen is found in human skin, bones, teeth, tendons, etc. Its main physiological function is to act as a binding substance for connective tissues. In the skin, it forms a mesh-like support body with elastin fibers, providing stable and strong support to the dermis. Collagen is a three-dimensional spiral structure of protein, very stable, to support the role of the skin, known as the “bone of the bone, skin of the skin”, is the skin dermis strong support, the skin is soft and smooth and elastic, mainly because of the collagen credit, the baby’s skin collagen content is sufficient. It can be said that all skin problems, such as wrinkles, aging, sagging, pigmentation and other conditions, are caused by the loss of collagen. As the body ages, the collagen content is gradually lost, and the mesh support body becomes thicker, harder, and less elastic. When the elasticity and water retention of the dermis decreases, the epidermis forms sagging wrinkles. For the average person, collagen loss begins after the age of 25. Women, in particular, lose collagen several times faster than men due to their physiological characteristics; consequently, calcium is also lost. It is especially important to supplement collagen for women around menopause. Therefore, it is very beneficial for women to take the right amount of collagen after they turn 25; of course, collagen injections are undoubtedly the fastest and most effective way to maintain the skin. SunMax collagen is technically supported by the Zyplast team, which started research and development in 1995 and set up a factory in Taiwan in February 2001. It is currently the only collagen product for injection that has been approved by the Chinese Drug Administration. V. Botulinum toxin BOTOX Injectable BTX-A botulinum toxin products are widely used in the medical beauty industry for power wrinkle elimination surgery, with the advantages of easy operation, non-invasive, good results, the beauty industry called: biological wrinkle removal technology. Evaluation: Botulinum toxin is cheaper and easier to operate. However, the duration of action is short, and repeated injections are required to maintain long-term effects.