1, age Throughout the ages and how many people cling to “immortality” the most useless, in the face of aging, an inevitable process of biological development, the kidneys are not immune. 40 years of age or older, every year, kidney function will decline 1ml, which is why as the population enters the aging of society, kidney function damage gradually increased one of the aspects of the people. 2, bad lifestyle The occurrence of chronic kidney disease is, in a way, also the result of social progress. Due to the rapid development of human society, lifestyle changes, hypertension, diabetes, dyslipidemia, hyperuricemia, obesity and other poor lifestyles lead to more and more of these “diseases of affluence”, and these problems are the high-risk factors that trigger kidney disease. Take hypertension for example, when hypertension is not controlled for a long time, it can lead to atherosclerosis of the small arteries of the kidneys, and the result in the long run is that the kidneys atrophy, sclerosis, and eventually will develop to kidney failure. Conversely, chronic kidney disease can not be controlled, kidney function continues to deteriorate, will also aggravate hypertension, which will enter a vicious cycle. 3, drug abuse Drugs have dual properties, if applied reasonably it can treat disease, if applied unreasonably not only does not cure the disease, and even the culprit of certain diseases. In particular, the liver and kidneys bear the brunt. Because the liver and kidneys are the body’s two most important organs for decomposition, metabolism and excretion of drugs, and the kidneys are known as the “human cleaning station”. Excessive and frequent abuse of drugs will make the drug concentration too high, and in serious cases can also be crystallized and deposited in the kidneys, thus damaging the normal function of the kidneys. Therefore, while not abusing antibacterial drugs, correct, reasonable and timely application of antibacterial drugs should also be emphasized. 4, Infectious diseases Certain infectious diseases, such as hepatitis, tuberculosis, schistosomiasis, and even the most common upper respiratory tract infections, etc. The immune response triggered by pathogenic viral or bacterial infections can cause primary or secondary renal diseases (such as glomerulonephritis, renal syndrome, etc.), which is also one of the important factors in the formation of chronic kidney disease, which is also a more specific trigger for chronic kidney disease in China. Therefore, it is also important to pay attention to hygiene in life and prevent infectious diseases. In addition, fast-paced life leading to excessive fatigue, unhealthy habits (high salt diet, addiction to smoking and alcohol, long-term urine holding, etc.) are all undesirable factors that induce chronic kidney disease. Tube chronic kidney disease is a lifelong disease, timely and effective treatment, it can still be controlled.