Many patients who have chronic kidney disease cannot be cured because of repeated illnesses and seek medical advice everywhere, believing in the so-called ancestral secret recipes or prescriptions, the disease not only does not improve, but also becomes more and more serious, accelerating the process of the disease, prematurely entering the uremic phase and requiring dialysis or kidney transplantation treatment, which hurts lives and money. Existing clinical research shows that the correct application of Chinese medicine can indeed play a role in delaying the progression of kidney disease and play a certain clinical efficacy. For example, rhubarb preparations can delay the deterioration of kidney function; thunderbolt polysaccharide has a significant therapeutic effect on glomerulonephritis; Cordyceps can protect kidney function; angelica, Chuanxiong and other blood-activating drugs can improve kidney circulation and make some of the residual kidney function repair. But at the same time, it should not be ignored that there are about 50 kinds of Chinese herbal medicines that may cause kidney damage, such as Mucuna pruriens, motherwort, celosia, petunia, make junzi, mountain cichlid, big green leaf, clove, zedoary, antifungal, whiteheaded wormwood, zebra, centipede, vermilion, etc. Some of these herbs are still commonly used in daily life, but they can only be applied at the discretion of kidney patients under the guidance of a specialist, while some are contraindicated. Some traditional Chinese medicines have been tested and found to be not as natural and non-toxic as one might think. For example, the gentian diarrhea of the liver pill was commonly used in the past because its formula, guanmutong, contained aristolochic acid, which caused aristolochic nephropathy, and the formula was changed for herb mouton. Chinese medicine has accumulated thousands of years of practice and has indeed provided clinical experience for the clinical treatment of chronic kidney disease. However, it is only in recent decades that there is a systematic and in-depth understanding of kidney diseases. The so-called “secret recipes” and “partial prescriptions” for the treatment of chronic nephritis, nephrotic syndrome and uremia are deceptive in many ways. Abusing Chinese medicine and misbelieving in prescriptions is like “lifting a stone to smash your own feet”.