In clinical practice, I often encounter patients and their families’ inquiries about related diseases, and while answering them, I can feel people’s urgent desire to obtain some basic knowledge about diseases. As the gastrointestinal tract is the main organ for obtaining nutrients from food, discomfort and diseases of the gastrointestinal tract are closely related to people’s quality of life, and gastrointestinal diseases are characterized by complicated diseases and high incidence, so it is especially important to popularize knowledge about gastrointestinal diseases and tell people how to prevent gastrointestinal diseases. In modern society, people’s life pressure has generally increased, and the pace of life has significantly accelerated, which has led to great changes in people’s habits, such as people’s eating habits are becoming more and more westernized and fast food, while on the other hand, with the improvement of the economic level, people’s diet structure has also changed greatly, more and more inclined to the intake of animal protein. These changes have gradually led to a quiet change in the incidence of many diseases, and the incidence of some so-called “diseases of affluence” is increasing year by year. For example, Crohn’s disease, the incidence of this disease was higher in Europe and the United States, the incidence in China is very low, but in recent years the incidence of this disease in China has gradually increased momentum. There are also tumors of the gastrointestinal tract such as gastric cancer, which is already a more familiar disease. Another example is gastrointestinal dysfunction, a disease that plagues many young people in their “right years” and which accounts for more than half of the outpatient visits to gastroenterology clinics in some hospitals due to increasing social and mental stress. Therefore, a healthy diet and lifestyle, combined with the adjustment of the mindset and the appropriate means of stress release, is essential for modern people to be able to stay away from gastrointestinal diseases. As with other natural sciences, if you want to conquer it, you must first understand it, and the same is true for gastrointestinal diseases. However, gastrointestinal diseases are complicated and involve many disciplines and specialties, and the development of modern medicine is not exaggerated by the word “rapidly changing”, so it is very difficult for ordinary people to have a comprehensive knowledge of gastrointestinal diseases. I hope to select some basic knowledge that I think people should know from a wide range of medical knowledge, mainly the causes of diseases, general manifestations and how to diagnose and treat, etc. Through the introduction of causes, I hope people can understand how to prevent diseases, through the introduction of disease manifestations, I hope people can detect some potential diseases as early as possible, and the introduction of diagnostic and treatment methods is hoped to facilitate patients or family members to communicate with medical staff and understand. I hope that the presentation of diagnosis and treatment will make it easier for patients or families to communicate with medical staff and understand their medical practices. I really hope that people can achieve the effect of “treating disease and preventing disease” after browsing my serials, but due to the limitation of my level, mistakes are inevitable and inevitably missing, so please criticize and correct my patients!