Abstract: Pulmonary embolism is a clinical and pathophysiologic syndrome of endogenous and exogenous emboli blocking pulmonary arteries causing pulmonary circulation disorders, with high incidence, morbidity, mortality and misdiagnosis. The main points of the monitoring of pulmonary embolism: 1, general care for highly suspected or confirmed PE patients should be quiet, absolute bedridden for 2-3 weeks, and pay attention to do not overflexion of the lower limbs; keep the bowel clear, avoid exertion, in order to prevent the lower limbs blood vessel pressure suddenly rise, so that the thrombus again off to form a new life-threatening embolism; and pay attention to the observation of respiration, heart rate, blood pressure, electrocardiogram and blood gas changes, once appeared Observe the respiration, heart rate, blood pressure, electrocardiogram and blood gas changes, and notify the physician at any time to deal with any changes in the condition. 2.For patients with hypoxemia, oxygen can be inhaled through nasal catheter or mask, after oxygen inhalation, the partial pressure of blood oxygen of most patients can reach more than 80mmHg, when combined with severe respiratory failure, continuous pressure non-invasive ventilation with mask or mechanical ventilation through tracheal intubation can be used, and the management of the respiratory tract can be done well. However, it should be noted that tracheotomy should be avoided to avoid local hemorrhage that is not easy to be controlled during anticoagulation or thrombolysis. 3, severe chest pain can be appropriate use of analgesic drugs, but if there are circulatory disorders, should avoid the application of vasodilating opioids, such as morphine, etc.; for anxiety and panic symptoms should be comforted and appropriate use of sedatives; in order to prevent intrapulmonary infections and phlebitis, in addition to aseptic operation, can be appropriate application of antibiotics, the presence of fever, cough symptoms can be given to the appropriate symptomatic treatment.