Acute pulmonary thromboembolism (PTE) is a clinically serious condition with an extremely high mortality rate, ranging from 10% in hemodynamically normal patients to 65% in patients requiring cardiopulmonary resuscitation. The most effective means of treating acute PTE is prompt recanalization of the occluded vessel. The traditional treatment is intravenous and/or oral anticoagulant therapy and intravenous pharmacologic thrombolysis. Anticoagulant therapy has a slow onset of action and incomplete thrombus removal, which can result in chronic pulmonary embolism and cause sequelae such as pulmonary hypertension; while systemic intravenous drug thrombolysis carries the risk of fatal hemorrhage in other organs (brain, gastrointestinal tract, etc.). Endovascular interventional therapy for PTE includes a variety of surgical procedures, mainly local thrombolysis, thrombus fragmentation, and thrombus aspiration via catheter to the embolized blood vessel. This method of local medication and/or mechanical removal of thrombus has a rapid onset of action and reduces the dose of systemic thrombolytic drugs, thus lowering the risk of hemorrhage in other organs. The main indications (meet one of the following criteria): (1) acute PTE combined with hypotension (systolic blood pressure of 40mmHg); (2) cardiogenic shock combined with hypoxemia; (3) circulatory failure requiring cardiopulmonary resuscitation; (4) alveolar-arterial partial pressure difference of oxygen > 50mmHg; (5) echocardiography suggestive of pulmonary arterial hypertension; (6) contraindications to anticoagulation and thrombolysis, the feasibility of mechanical thrombectomy. Deep vein thrombosis is closely related to PTE and can be combined with various organ and limb dysfunction, so it needs to be actively handled, and the interventional treatment includes transcatheter endovascular local thrombolysis, thrombus fragmentation, thrombus suction and angioplasty. Meanwhile, in order to prevent deep vein thrombus from dislodging into the pulmonary artery and causing PTE, vena cava filter placement is needed. The indications for vena cava filter placement include: (1) classical indications for venous thrombophilia (pulmonary embolism, thrombosis of inferior vena cava, iliac veins and lower extremity veins) combined with one of the following three conditions: (a) contraindication to anticoagulation, (b) complications of anticoagulation, (c) failure of anticoagulation; (2) recognized indications for (a) massive PTE with residual DVT, (b) severe cardiopulmonary diseases combined with DVT, (c) severe cardiopulmonary diseases combined with DVT, and (d) serious cardiac and pulmonary diseases combined with DVT, and (e) serious cardiopulmonary diseases combined with DVT. (b) severe cardiopulmonary disease combined with deep vein thrombosis, (c) poor compliance with anticoagulation therapy for PTE; (3) extended indications are for those who are at high risk (e.g., severe trauma, prolonged braking and intensive care, preoperative surgical procedures with multiple risks of venous thrombosis, and during treatment for deep vein thrombosis, etc.) but who have not yet developed PTE. The characteristics of our hospital: (1) the opening of a green channel to give patients the most timely treatment; (2) pulmonary embolism and deep vein thrombosis at the same time to ensure the efficacy of interventional therapy, and according to the indications for vena cava filter placement, and at the same time, feasible to measure the pressure of the pulmonary artery; (3) the respiratory department of the hospital has a wealth of experience in anticoagulant therapy for PTE, and fully combined with the internal medicine and interventional therapy, to improve the effectiveness of the treatment.