Penile sclerosis is an inflammatory disease that occurs in the white membrane of the penis and has an unclear etiology. It is characterized by striated or plaque-like hard nodules on the dorsal side of the penis. The plaques are cartilage-like in texture and are painful to the touch, with the penis bending during erection and painful during intercourse. It is equivalent to what Chinese medicine calls “phlegmatic nucleus of the penis”. Also known as nodular cavernositis, Peyronie’s disease, penile fibrous cavernositis. So advocate cleanliness, stay away from prostitutes, pay attention to daily hygiene and wash your hands regularly. If there is frequent urination, painful urination or urethral discharge, there may be urinary tract infection, which should be treated promptly and not leave the root of the disease. Guangzhou University of Traditional Chinese Medicine Shenzhen Affiliated Hospital Male Department Gu Yu Neng 2, avoid trauma: severe trauma or repeated tiny trauma can cause fibrosis of the white membrane of the penis and produce hard nodes. Therefore, when carrying out various types of urethra, penile examination or surgery (such as urethral intubation, circumcision, penile orthopedics, etc.) require doctors to operate carefully to avoid excessive injury. Pay attention to protecting yourself during physical exercise, especially the more strenuous sports such as soccer and combat, to prevent the penis from being hit and squeezed, and to prevent injuries to the pubic area. Daily life to prevent strong acid, strong alkali caused by pubic burns, cold weather areas to prevent frostbite. 3, sexual life moderation: excessive intercourse damage the yin qi and blood and the development of this disease, so sex should be moderate, the strength of the line, and to eliminate violent sexual intercourse. Young men should try to abstain from masturbation. 4, scientific diet: if the diet is not controlled, damage to the spleen and stomach, spleen deficiency phlegm, phlegm cohesion penis also become hard knots. The actual fact is that you will be able to get a lot more than just a few of the most popular and most popular items. The first thing you need to do is to get rid of the pain, and also cause the couple to have an uncoordinated sex life, which has a big impact on the male psyche. Early treatment can reduce pain, soften the fibrous plaque and prevent further bending of the penis. Generally, the following aspects can be chosen to implement early treatment. 1, pay attention to rest, suspend all intercourse and sexual stimulation. 2, a light diet, avoid smoking, alcohol and spicy stimulating food. 3, pain when taking colchicine 0.5mg ~ 1mg / time, can be anti-inflammatory and pain relief. 4.Vitamin E can increase the resistance of skin capillaries, prevent excessive oxidation of cell membrane lipids and slow down the aging process. Dosage: 100mg per time, 3 times daily orally for 3-6 months; or 300mg per time, once daily for 6-9 months. 5. Potassium para-aminobenzoate, 12g daily, divided into two doses, for 6 months to 1 year. Or Procarbazine (mebendazole), 50mg each time, taken orally twice a day for 3 months. 6.Injecting adrenocorticotropic hormone into the hard nodes, such as Coninectone A 40mg, once a week for 2 weeks. 7.Chinese herbal tonics for internal use. Commonly used prescriptions include Orange Kernel Pill, Yang He Tang, etc. Third, surgical treatment Penile sclerosis if early failure to treat, mis-treatment, can make the plaque expand, pain increased, penile erection after degeneration, bending, affect the quality of sexual life, or even completely lose the ability to have sexual intercourse. Surgery is required for patients with longer duration of disease, serious condition or ineffective conservative treatment. Surgical treatment includes correction of penile curvature and removal of plaque in two parts. Fourth, daily attention Pay attention to rest and recuperation, restraint in sexual intercourse; diet science, take sufficient nutrition and vitamins, such as more green leafy vegetables; pay attention to foreskin cleaning, underwear should be loose, soft.