I. Introduction of the disease: penile sclerosis is a fibrotic lesion of the white membrane of the penile corpus cavernosum, causing single or several patches or hard nodules to appear on the dorsal or lateral side of the penis. There is no specific medicine for this disease, and drug treatment is generally anti-fibrotic, with a long course of disease and poor treatment effect. When the erectile deformity of the penis is obvious, surgery can be considered to remove the sclerotic node, and the defect needs to be covered by transplanting skin tendon membrane, sheath or oral mucosa. Basic information: Patient Xiao Liu, male, 52 years old, general worker, junior high school education, usually does not smoke or drink, and has good living habits. Medical history: Xiao Liu found by chance a hard lump on the left side of the root of his penis 3 years ago when taking a bath, about the size of a grain of rice, not painful or itchy, and able to have a normal erection. There is no pain during erection, so he did not pay attention to it at that time and did not seek medical attention. In the past year, it is obvious that the hard lump has gradually increased in size and is now the size of a soybean, and when the penis is erect, it is found to be skewed to the left side. Fourth, the specialist examination: penis development is normal, the left side of the penis root can be touched about 1.0 × 37.5px hard nodes, clear boundary, hard texture, mild tenderness. The right side of the penis was normal. V. Preliminary diagnosis: penile sclerosis.