There is no such thing as the fastest way to stop a runny nose in clinical practice. The cause of runny nose may be due to cold, bacterial infection, viral infection and allergic rhinitis, etc. General treatment, anti-bacterial treatment, anti-viral treatment and anti-allergy treatment can be used to stop runny nose. 1. General treatment: If the runny nose is caused by cold, you should add clothes in time when it is cold, apply hot towel to the forehead, and rinse the nasal secretion with saline, which can clean the nasal cavity and relieve excessive nasal secretion. 2. Anti-bacterial treatment: bacterial infection caused by rhinitis resulting in a runny nose, often use antibiotic drugs, such as amoxicillin, cefaclor, etc.. 3. Antiviral treatment: If the runny nose is caused by viral infection, it is usually necessary to treat the symptoms, and serious cases can take antiviral drugs, such as ribavirin. 4. Anti-allergy treatment: If the runny nose is caused by allergic rhinitis, avoid contact with allergens, and take anti-allergy drugs as prescribed by the doctor, such as loratadine, montelukast sodium and so on. Patients with symptoms of runny nose, if the symptoms are not relieved by the general treatment, you should consult a doctor in time to clarify the cause of the disease, under the guidance of the doctor for medication and standardized treatment.