Precautions for adult hepatitis B vaccination include being healthy at the time of vaccination, being on time for the whole vaccination, knowing the contraindications of vaccination, and keeping hygiene of the vaccination site. 1. Be healthy at the time of vaccination: Adults should be healthy at the time of hepatitis B vaccination, and should not have fever and other conditions. 2. Vaccinate on time: Hepatitis B vaccination needs to follow the principle of 0, 1, 6, i.e. the first vaccination, the second vaccination one month after the first vaccination, and the third vaccination six months later. 3. Understand the contraindications of vaccination: those who suffer from dermatitis, purulent skin disease, severe eczema; those who suffer from serious heart, liver, kidney disease and active tuberculosis; those who suffer from abnormal brain development and epilepsy; and those who suffer from severe allergy can not be vaccinated with hepatitis B vaccine. 4. Keep the vaccination site hygienic: after the injection of hepatitis B vaccine, the vaccination site must be kept hygienic, it is best not to scrub within three days after the vaccination to avoid scratching and causing local infection.