A female patient was seen for appendicitis, which was surgically confirmed to be septic appendicitis, and the appendix was removed and recovered successfully. The cause of intestinal obstruction was due to colon tumor. Zhu Jianwei, Department of Gastrointestinal Surgery, Nantong University Hospital A male patient with right lower abdominal pain visited the hospital with obvious signs and was initially diagnosed with appendicitis, and then received surgical treatment, during which he saw an edematous and congested appendix with inflammation, but also saw a dilated and inflated cecum with obvious suspicion of obstruction. A male patient, who often complained of right lower abdominal pain, was diagnosed with chronic appendicitis in the lower hospital, and improved with anti-inflammatory treatment, but soon recurred. Later, a barium enema was done and a tumor was found in the ascending colon. Surgery confirmed the presence of colon cancer. A female patient was operated urgently for “appendicitis”, and it was found that there was no problem with appendix, but cecum tumor with perforation.