The standard vaccination regimen for adults who have not been vaccinated against Hepatitis B is 3 shots; those who have been vaccinated before may be given 1 supplemental shot as appropriate. Hepatitis B vaccine is a vaccine that protects against viral hepatitis B and stimulates the immune system to produce protective antibodies against Hepatitis B. The vaccine is administered to adults who have not received the Hepatitis B vaccine. For adults who have never received hepatitis B vaccine and have not produced protective antibodies, the standard vaccination program is to receive 3 doses of hepatitis B vaccine on the day of vaccination, 1 month later and 3 months later. Standardized and complete vaccination can better produce protective antibodies and play a preventive role. If you have been vaccinated with hepatitis B vaccine in the past, you can improve the quantitative examination of hepatitis B 5 items to clarify the concentration of hepatitis B antibody. When the concentration of hepatitis B surface antibody (HBsAb) is lower than 10mIU/ml, you need to take a supplementary shot of hepatitis B vaccine, and one month after the vaccination you can recheck the concentration of hepatitis B surface antibody, and if it is higher than 200mIU/ml, you can no longer take the injection, and if the antibody level is lower, you can consider to take a second supplementary shot to produce the effective concentration of protective antibody, and produce protective antibody in 3 months. If the antibody level is low, the second injection can be considered in order to produce effective concentration of protective antibody, and pay attention to the recheck. The injection program of adult hepatitis B vaccine needs to be chosen according to specific conditions, and it is recommended to consult doctor in time and choose reasonably under doctor’s guidance.