Low urine osmolality can be seen in physiological conditions such as excessive water intake, generally no special treatment, regular review can be. Pathological conditions can be seen in renal tubular-interstitial injury diseases, such as hypertensive nephropathy, gouty nephropathy, acute interstitial nephritis, etc., need to target the specific causes of treatment. 1. Physiological conditions: such as drinking too much water, can lead to dilution of urine, urine routine examination can be seen in urine osmolality is low. 2. Pathological conditions: reduced urine osmolality often suggests tubular-interstitial injury disease, resulting in renal concentration, dilution function injury, common diseases such as hypertensive nephropathy, gouty nephropathy, interstitial nephritis. It is necessary to follow the doctor’s instructions to improve the relevant examination, for specific causes, give targeted treatment. Patients with low urine osmolality are advised to go to regular hospitals in a timely manner and receive standardized treatment under the guidance of a physician.