The individual variation of menopause in women is related to many factors. The average age of menopause in Chinese women is 49~50 years old, and the natural cessation of menstruation before the age of 40 is considered premature menopause, which is clinically known as premature ovarian failure. So, what are the dangers of early menopause and how to prevent it? 1, osteoporosis Because of the decline of ovarian function, estrogen levels decline, affecting the deposition of calcium in the bones, so it is easy to lead to osteoporosis. Now it is possible to detect and diagnose osteoporosis early through bone density measurement. Ma Hongxia, Department of Traditional Chinese Medicine, The First Hospital of Guangzhou Medical University Response: No safe and effective method has been found to rebuild the already osteoporotic bones. Drug treatment can only slow down and end bone loss. Therefore, prevention is more important than treatment for osteoporosis. For example, strengthen exercise, especially regular weight-bearing exercise; pay attention to calcium-rich diet, such as milk, soy products, dried fruits, cauliflower, radish, cabbage, etc., and supplement calcium and vitamin D when necessary; develop good habits, do not smoke, drink less alcohol, do not drink coffee, more sunshine; pay attention to self-protection, avoid bruises. 2, genitourinary system diseases Due to low estrogen levels, the female genitourinary system will undergo a series of degenerative and atrophic changes. For example, thinning of the vaginal epithelium and relaxation of the pelvic muscles can cause displacement of the urethra and bladder; thinning of the vaginal mucosa and low resistance to infection can lead to atrophic cystitis, urinary incontinence, urethritis and senile vaginitis. Countermeasures: Prevention and treatment should be combined for the genitourinary system diseases caused by this. Topical estrogen ointment topical application and hormone replacement therapy can prevent recurrent urinary tract infections and senile vaginitis, as well as common diseases of the genitourinary system. Anal lifting exercises and pelvic floor muscle exercises can improve urinary symptoms. In addition, it is important to pay attention to personal hygiene, keep the vulva clean and change underwear regularly; insist on participating in appropriate exercises to enhance physical fitness and slow down aging. For uterine prolapse, anterior and posterior vaginal wall (bladder, rectum) bulge with urinary disorders, surgical treatment can be performed. 3, cardiovascular disease Estrogen can improve the elasticity of blood vessels, making them less prone to hardening and blockage. Therefore, the decrease in estrogen level caused by early menopause will cause abnormal blood lipid metabolism and make cardiovascular diseases easier to occur. Countermeasure: Combine prevention and treatment. At present, the more effective method is hormone replacement therapy, specific drugs and doses must be taken under the guidance of a doctor, and it is recommended to treat with this therapy until the age of 45. (1) Diet should be light, less salt, low sugar, more vegetables, fruits, soy products, a certain amount of lean meat, fish and shrimp and eggs. (2) Do not stay up late, stop smoking and limit alcohol, limit weight, and exercise appropriately. (3) good at regulating emotions, avoid mental tension, maintain a calm state of mind. After working under stress, you can listen to music, read books, go on trips, etc., and learn to relax. (4) Follow medical advice and take medication. 4.Menopausal syndrome Due to the interaction of various endocrines, the phenomenon of phytodysfunction may occur, resulting in vasodilator dysfunction, which is commonly known as menopausal syndrome, manifested as hot flashes, sweating, palpitations, dizziness, fatigue, inattention, depression, tension, emotional instability, agitation, dizziness, tinnitus, panic, etc. Countermeasures: The degree of performance of these symptoms varies greatly among individuals, most of them will gradually subside and disappear, and in severe cases, hormone replacement therapy and Chinese medicine can be used to improve the symptoms. In addition to this, the mental state should not be ignored. Due to early menopause, it is easy to have psychological imbalance, fear, low self-esteem, complaints and anger, and various physical discomfort, which will aggravate the accumulation of bad emotions, resulting in irritability, anxiety, and even depression. Therefore, premature menopause needs to be treated correctly, overcome fears, learn more about the disease and strengthen exercise; families should give support and seek help from psychologists if necessary to smoothly pass this period.