1.Local emergency treatment Wash the contaminated skin with soap solution and running water, and rinse the mucous membrane with saline. If there is a wound, it should be gently squeezed at the side end of the wound, squeeze out the blood at the injury as much as possible, and then rinse with soap and running water; it is forbidden to carry out local squeezing of the wound. After rinsing the wound of the injured part, it should be sterilized with disinfectant, such as 75% alcohol or 0.5% iodophor, and the wound should be bandaged; the exposed mucous membrane should be repeatedly rinsed with saline. 2.Inject hepatitis B immunoglobulin as early as possible Hepatitis B immunoglobulin (HBIG) provides temporary passive protection. HBIG is made from concentrated and purified human serum containing hepatitis B surface antibody (anti-HBs), and should be injected within 24 hours after exposure if the source of exposure is known to be HBsAg-positive, and the dose of HBIG injected should be 0.06ml/kg of body weight. 3.Hepatitis B vaccination Hepatitis B vaccine can be injected intramuscularly at the same time or within 7 days after contact. Specific method: intramuscular injection in the deltoid muscle of the upper arm, the dose is 20ug each time for a total of three injections, the time is 0, 1, 6 months, and after completing the injection, it can be detected whether the antibody (anti-HBs) is produced or not.