I. Overview The diabetic foot is defined as the foot of a diabetic patient with inadequate blood supply due to vascular disease, sensory loss due to neuropathy, and co-infection. According to the definition of the International Diabetes Federation, the diabetic foot has three factors, the first factor is vascular, the second factor is nerve, and the third factor is infection. Second, the etiology of diabetic patients are prone to diabetic foot because they have a variety of metabolic disorders. Including high blood sugar, high blood pressure, poor blood supply, in addition to high blood lipids, high blood viscosity, easy to block blood vessels, and therefore easy to lead to diabetic foot. Third, the clinical manifestations of diabetic foot is a developmental process, neuropathy and vascular lesions have been occurring to a certain extent into a diabetic foot. 1, intermittent claudication Because of the poor blood supply to the blood vessels, it is not possible to walk for a long time, and after walking for a period of time the foot will feel painful and must stop to rest. If you insist on walking at this time, claudication will occur, which can be restored after rest. This condition is called intermittent claudication, which means that the blood vessels are already blocked by 60% to 70%. If the blood vessel is further blocked, 80% to 90% blockage will occur “rest pain”. 2, rest pain does not need to walk that is to happen vascular blood supply is not good, the patient will sleep through the night, pain is unbearable. Further progress, the foot will break down. 3, diabetic gangrene gangrene is necrosis, commonly known as “rotten feet”. Poor blood supply is prone to infection, easy ischemia, easy to break down, bad nerves do not feel sensitive, the occurrence of ulcers do not know, with the wound, the infection does not feel pain, so it is easy to ignore this infection. If the infection is serious, the patient’s foot to perform amputation. Fourth, prevention Diabetic patients should often check the foot. For example, check whether the skin color of the foot is normal. If the artery is ischemic and the foot is lifted, its skin color will turn white. If the foot is sagging and the veins are bad, the skin of the foot will turn purple. You can check the feeling of the foot by pricking the foot with cotton or nylon silk on a daily basis. If it feels bad and lacks protection, the foot is prone to breakage. Also check the integrity of the hair of the foot, poor nutrition will cause the loss of hair on the foot. To frequently check the foot for breakage and bleeding. Pay attention to the protection of the foot. Pay attention to keeping your feet clean and dry, as clean is less prone to infection and dry is less prone to tinea pedis. Pay attention when wearing shoes: don’t have foreign objects in your shoes. It is best to buy socks in light colors to make it easier to observe abnormal conditions of the feet, and the texture of the socks should be smooth. You can soak your feet properly. When soaking your feet, you must pay attention to: make sure to test the water temperature with your hands first, because your hands are sensitive and the water should not be too hot, as other problems can easily happen if you burn your feet. Patients should cooperate with their doctors, which can make the diabetic foot happen later and avoid amputation.