There are many accidents in life that often happen without notice. According to the survey, many people suffer from cranial defects due to an accident or a natural or man-made disaster, thus dealing a heavy blow to their health. Cranial defect is a major issue, if not repaired as soon as possible, it will not only have a great impact on the external appearance of the person, but also the brain tissue will easily suffer from secondary injury due to the loss of normal cranial barrier protection, and it may also cause other complications. Therefore, when we have a skull defect problem, we have to restore our skull to integrity through cranial bone repair surgery. But how to calculate the size of skull defect? When is the right time to perform skull repair? This has become the most important concern for many patients during the repair process. It is understood that for the indications and timing of cranial repair, the neurosurgical guidelines stipulate that when the defect area is larger than 3 cm and there is no contraindication, the patient can be repaired 2-3 months after debridement. Some patients may also depend on their actual situation. For example, when Hope was missing her skull at the age of 9, the local hospital recommended repair after the age of 18. However, in the two years after the skull, Xiao Yuan suffered a lot of disturbances in her normal growth, life and study, which also made her parents speed up the pace of getting her skull repaired. Through online research, the parents learned that our team is very professional in skull repair, and after years of dedicated research and clinical practice, we now have excellent surgical skills and rich clinical experience. Our team is currently carrying out peek skull repair plastic surgery, which has achieved very good results in the clinic. So she came to the hospital for treatment in July 2019. After detailed diagnosis, we found that Xiao Yuan had a total of three defects in her head, and all of them were irregular in shape, and developed a personalized and refined treatment plan. Then we performed PEEK cranioplasty for her skull repair. During the operation, three pieces of PEEK material were precisely cut into the bone window to achieve good anatomical repositioning. After the surgery, Xiao Yuan’s head looked not much different from before and she was in a good mood.