The difference between nephrogenic edema and cardiogenic edema: First, the etiology is different, nephrogenic edema is caused by kidney disease, while cardiogenic edema is caused by heart disease. The clinical manifestations are different. The early stage of nephrogenic edema is seen as edema of both eyelids, and as the condition worsens, edema of both lower limbs or even the whole body may slowly appear. In patients with cardiogenic edema, the edema of both lower extremities appears at the beginning, and if the disease is serious, it may lead to generalized edema. Third, nephrogenic edema may be combined with hematuria, proteinuria, hypertension and even elevated blood creatinine and urea nitrogen. For patients with cardiogenic edema, there will be a combination of panic, chest tightness and dyspnea. Patients with nephrogenic edema can be treated with kidney-protective drugs and diuretics, while patients with cardiogenic edema can be treated with diuretics and cardiotonic drugs.