Redness and erythema of the cheeks in the evening may be related to fever, tuberculosis, menopausal syndrome, contact dermatitis, rosacea and other diseases, which need to be treated with antipyretic, anti-tuberculosis, hormone supplementation, anti-allergy and anti-inflammatory drugs. 1. Fever: for different causes of fever which leads to facial erythema and redness, the main treatment is to address the cause of the disease, and then give symptomatic antipyretic treatment, such as viral infections caused by fever, given to the anti-viral treatment of compound aminophenol alkylamine capsule; bacterial infections caused by fever, the choice of antibiotic treatment, such as amoxicillin capsule. 2. Tuberculosis: For lung diseases caused by Mycobacterium tuberculosis infection, sensitive anti-tuberculosis drugs need to be taken, such as rifampicin, isoniazid, pyrazinamide, ethambutol and so on. 3. Menopausal syndrome: for a series of symptoms caused by the level of hormone secretion in the body, it can be treated by hormone supplementation, such as estradiol valerate, medroxyprogesterone acetate and so on. 4. Contact dermatitis: for allergic reactions due to contact with certain irritating substances, the main treatment is to give anti-allergic drugs, such as loratadine. 5. Rosacea: a chronic inflammatory skin disease that occurs in the center of the face and is treated with anti-inflammatory drugs such as doxycycline hydrochloride. It is recommended that patients go to the hospital in a timely manner, after a clear diagnosis under the guidance of the doctor to standardize the treatment, the use of drugs need to follow the doctor’s instructions, avoid self-medication.