When a patient’s urine is positive for both urobilinogen and urinary bilirubin, the possibility of hepatocellular jaundice is most likely to occur. Then urobilinogen enters the bloodstream and is excreted in the urine through the kidneys. In addition, when the liver function is impaired, after the patient’s liver cells are necrotic, the patient cannot take in direct bilirubin normally, resulting in an increase in direct bilirubin in the blood, which can also be filtered through the glomerulus and excreted by the kidneys in the urine, resulting in a positive urobilinogen and urinary bilirubin. In this case, patients need to be actively treated with hepatoprotective therapy and etiological treatment according to the cause of the disease.