Stress cardiomyopathy, also known as ballooning of the heart, is also referred to by some as broken heart or heartbreak syndrome. This disease is associated with a high degree of emotional stress or mental stimulation. The onset of the disease can be similar to acute myocardial infarction, and the clinical presentation is similar to that of dilated cardiomyopathy, which is less common in clinical practice. Today, we will discuss the treatment of stress cardiomyopathy. Patients may experience sudden onset of pain in the precordial region and posterior back during an attack, which may be accompanied by electrocardiographic changes, either with or without st-segment elevation or depression, or with or without t-wave inversion. Coronary angiography is often performed before the diagnosis is confirmed in order to further rule out the possibility of acute coronary syndrome. Cardiac angiography or echocardiography can show mid-ventricular and apical dilatation. However, clinical symptoms are often transient in nature and treatment is primarily symptomatic support with appropriate reassurance. The preferred therapeutic agents are mainly beta-blockers. beta-blockers, which help to suppress sympathetic excitability, slow down the patient’s heart rate, and reduce myocardial oxygen consumption relieve the symptoms of anterior cardiac region as well as posterior back discomfort. This disease often occurs after a major life event, such as the death of a loved one or an earthquake, or after an invasive surgical procedure, etc. Patients with significant anxiety or depression can also be improved with a combination of psychiatric medications. Currently, the clinical treatment of cardiac patients is increasingly focused on psychological treatment. In addition to improving the patient’s organic pathology, it is also necessary to combine psychological support and emotional improvement with symptomatic treatment.