OVERVIEW
OVERVIEW
Sulfated hemoglobinemia is a disease in which sulfated hemoglobin appears in the blood. Once generated, hemoglobin sulfide can not be restored to hemoglobin. Since hemoglobin sulfide can not carry oxygen, clinical symptoms of hypoxia such as cyanosis, dizziness, headache, shortness of breath, etc., usually without respiratory dysfunction. Some drugs that can produce methemoglobin can also produce hemoglobin sulfide, such as sulfa drugs, finasteride, nitroglycerin and other drugs, and exposure to toxic substances such as sodium nitrite and potassium nitrate can cause this disease.
Whether medical insurance
Yes, it is
Department
Hematology
Clinical symptoms
Cyanosis, dizziness, headache and shortness of breath.
Harm
Dizziness and headache may occur, thus affecting normal life.
Examination
Physical examination, sulfated hemoglobin measurement, etc.
Diagnosis
Diagnosis can be made on the basis of history, cyanosis, dizziness and hemoglobin sulfide measurement.
Treatment principle
No specific treatment is required as most patients have minor clinical symptoms. When symptoms are severe, bloodletting or blood exchange therapy may be used. There are no drugs available to treat this disease.
Curability
Most can be cured.
Dietary advice
Eat a nutritious diet, small and frequent meals, and increase the amount of water intake appropriately.
Causes
Etiology
Related to taking certain drugs or exposure to toxic substances or other causes.
Symptoms and Diagnosis
Typical symptoms
Slow onset, cyanosis is the main clinical manifestation, severe cases may have dizziness, headache, even shortness of breath, fainting; some patients may be due to constipation, diarrhea and other causes of the onset of the disease, may be accompanied by the above symptoms and other manifestations.
Diagnostic basis
1. patients have a history of taking drugs such as sulfonamide or exposure to toxic substances, etc. 2. slow onset, with cyanosis, dizziness, headache, shortness of breath, etc. 3. increased sulfated hemoglobin in the blood.
Treatment
Treatment guidelines
There is no effective drug cure yet, symptomatic treatment such as diarrhea can be carried out, and bloodletting or blood exchange therapy can be adopted when the symptoms are severe.
Drug treatment
1. There is no effective drug treatment, the formation of sulfated hemoglobin is irreversible to normal hemoglobin until it is cleared, which often takes several months, methylene blue, vitamin C, etc. are ineffective in this disease. 2. Those who are constipated can use diarrhea-conducting drugs, but should not be treated with magnesium sulfate.
Other treatments
In severe cases, intravenous bloodletting therapy, or blood exchange therapy may be considered.
Prognosis
Most of them have good prognosis.
Nursing care
Daily care
1. Maintain the environment at a suitable greenhouse level and ventilate frequently.2. Rest and activitiesPatients should have sufficient rest, live a regular life, avoid exertion, take activities as long as they don’t feel fatigue, and maintain sufficient sleep to prevent aggravation of the condition.3. Psychological careFamily members take the initiative in communicating with the patient to promote the interaction between the patient and family members, and participate in caring for the patient on their own initiative to alleviate the depression within the patient’s heart.4. Periodic Review and consult the doctor promptly if there is any discomfort.
Dietary management
Nutrient-rich diet, small meals, increase water intake appropriately.