Cerebrovascular blockage, i.e. cerebral infarction and cerebral thrombosis, has high incidence, high recurrence rate and high disability rate, and the treatment of cerebrovascular blockage should choose the best treatment method according to different onset periods, etiology and pathogenesis. Ultra-early stage: treatment of vascular unblocking should be carried out as early as possible to improve the blood supply in the ischemic area by means of restoring blood flow to achieve the purpose of saving brain cells. At present, there are various treatment methods, such as intravenous thrombolysis (rt-PA thrombolysis within 4.5 hours of onset and urokinase thrombolysis within 6 hours of onset), arterial thrombolysis and intravascular intervention to retrieve emboli. Acute phase: In the acute phase of cerebrovascular blockage, the condition is unstable and easy to progress and aggravate, so it should be hospitalized. Cerebrovascular blockage is usually caused by atherosclerosis of the patient’s blood vessels, so it is appropriate to adopt antiplatelet aggregation and lipid-lowering treatment to stabilize plaque in the acute phase, and supplemented with comprehensive treatment measures such as improving cerebral circulation and nourishing brain cells to save brain tissue and preserve brain nerve function as much as possible. Severely ill patients should be treated with neurological monitoring. Recovery period: Patients in the recovery period mainly focus on neurological function recovery and control of risk factors, and rehabilitation therapy should be actively carried out, which can be accompanied by comprehensive therapeutic measures such as Chinese medicine and acupuncture to restore damaged neurological functions and alleviate sequelae. Posterior period: rehabilitation treatment is still the focus, maintaining a good state of mind, strengthening the training of daily living ability and improving the self-care ability of seriously ill patients, meanwhile, attention should be paid to improving lifestyle, controlling risk factors and actively preventing recurrence. In conclusion, there is no set treatment for cerebrovascular blockage. At present, ultra-early thrombolysis and endovascular intervention within the time window is the best treatment, however, this time is very limited, and the treatment of cerebrovascular blockage should choose individualized treatment plan and comprehensive treatment according to the etiology and onset time.