Treatment of advanced lung cancer
1. Chemotherapy The commonly used chemotherapy regimens are: Guo Zhifeng, Department of Medical Oncology, Chifeng Hospital Guo Zhifeng, Department of Medical Oncology, Chifeng Hospital
I. Non-small cell lung cancer
MAP regimen —– repeated every 28 days
Mitomycin 8MG/M2 IV Day 1,5,10
Vincristine 3MG/M2 IV Day 1,9
Cisplatin 120MG/M2 IV Day 1,5
CAP regimen ——– Repeat on day 28
Cyclophosphamide 400MG/M2 IV day 1
Adriamycin 40MG/M2 IV Day 1
or
Epiampicillin 60-80MG/M2 IV Day 1
Cisplatin 100MG/M2 IV Day 1
CE regimen ——- Repeat on day 21
Carboplatin 325MG/M2 IV Day 1
Pedialyte glycosides 100MG IV Day 1-5
NP regimen ——– 1 cycle every 4 weeks
Vincristine (Norviben) 25-30MG/M2 IV days 1,8,15,22,29
Cisplatin 120MG/M2 IV day 1,29
ICE regimen ——- repeated every 28 days
Isocyclophosphamide 1G/M2 IV Day 1 (3 hours)
MESNA 500MG/M2 IV 0,4,8,12 hours (after IFO treatment)
Podophyllin 100MG/M2 IV day 1-3
Carboplatin 120MG/M2 IV day 1-3
PC regimen ——- repeated every 21 days
Paclitaxel 135-175MG/M2 IV Day 1
Carboplatin AUG6.0-7 IV Day 2
MIP regimen —— Repeat every 21 days
Mitomycin 6MG/M2 IV Day 1
Isocyclophosphamide 3G/M2 IV (three hours) Day 1 (with MESNA to prevent hemorrhagic cystitis)
Cisplatin 50MG/M2 IV Day 1
EP regimen + radiotherapy —-21 days repeat
Week 1 2 3 4 5 6 7 8
Days 1 8 15 22 29 36 43 50
Cisplatin ^ ^ ^ ^ ^ (40MG/M2)
Pedialyte glycosides (50MG) oral capsule 50MG every other day and twice every other day
Radiotherapy (1.2GY) (total 69.6GY) for 6 weeks at 1.2GY per day, 5 days per week
T+ radiotherapy regimen
Paclitaxel 60MG/M2 IV 1 time per week*6 (three hours)
Radiotherapy 60GY for primary site and chemotherapy*6 weeks
Lymph nodes 40GY
PC regimen + radiotherapy —— repeated every 21 days
Paclitaxel 50MG/M2 IV 1 time per week
Carboplatin AUG2.0 IV 1 time per week
Radiotherapy 2GY/day IV 5 weekly total 66GY
Started 3 weeks after radiotherapy
Paclitaxel 175MG/M2 IV Day 1
Carboplatin AUG6.0 IV Day 1
Doxorubicin monotherapy regimen —–21 days repeat
100MG/M2 IV Day 1
DP regimen ——–21 day repeat
Doxorubicin 75MG/M2 IV Day 1
Cisplatin 75MG/M2 IV Day 1
DN regimen ——–25 day repeat
Doxorubicin 75MG/M2 IV Day 1 (oral demi 8MG*3 the day before start)
Vincristine 25MG/M2 IV Day 1,8
II. Small cell lung cancer
CAV regimen ——–21 day repeat
Cyclophosphamide 1G/M2 IV day 1
Adriamycin 45-50MG/M2 IV Day 1
Vincristine 1MG/M2 IV Day 1
CE regimen ——21 day repeat
Carboplatin 100MG/M2 IV Day 1-3
Pedialyte glycosides 120MG/M2 IV Day 1-3
COME regimen ——21 days repeat
Cyclophosphamide 750MG/M2 IV Day 1,8
Vincristine 1MG/M2 IV day 1,8
Methotrexate 20MG/M2 IM/IV day 3.5.10.12
Pedialyte glycosides 100MG IV days 3-7
POV protocol —-21-28 days repeat
Podophyllin 200MG PO Days 1-5
IEP regimen —–21 days repeat
Isocyclophosphamide 1.2G/M2 IV Days 1-4
Podophyllin 75MG/M2 IV Days 1-4
Cisplatin 20MG/M2 IV Days 1-4
CPE regimen —–21 days repeat
Carboplatin AUG 5 IV Day 1
Paclitaxel 135MG/M2 IV Day 1 (1 hour)
Pedialyte glycosides 50MG PO days 1-10
100MG PO every other day for 10 days
CODE protocol ——–21 Repeat on day 1
Cisplatin 25MG/M2 IV 1 time per week*9
Vincristine 1MG/M2 IV 1 time each week 1.2.4.6.8
Adriamycin 40MG/M2 IV once each week 1.3.5.7.9
Pedialyte 80MG/M2 IV 1 day a week for weeks 1.3.5.7.9
80GM/M2 PO Weeks 1.3.5.7.9, 2.3 days per week
Single agent TOPOTECAN regimen —— repeated every 21 days
TOPOTECAN 1.25-1.5 MG/M2 IV (30 min) Days 1-5
2. If chemotherapy fails, biologic targeted therapy such as Erythropoietin, Troche etc. can be used, which has good efficacy for lung adenocarcinoma.
3. For patients with squamous lung cancer, radiotherapy can improve the efficacy of chemotherapy.
4. Chinese medicine can be used as an adjuvant treatment, but do not rely on Chinese medicine alone. Nowadays, there are many websites on the internet that advertise how good and spiritual the herbal medicine is, which are all advertisements.