Central exudative chorioretinopathy’ is referred to as ‘central exudative’. It occurs in young and middle-aged people, from their late teens to their 40s, and its symptoms are mainly vision loss and visual distortion. It is caused by abnormal neovascularization of the macular choroid, which causes repeated bleeding and exudation and eventually leads to irreversible structural damage of the macula. The etiology of the disease is unknown, some people think it is related to tuberculosis and viral infection, and if there is indeed infection, appropriate treatment should be taken. However, most of the patients we encountered in our clinical work could not find a clear etiology. At present, the treatment of neovascularization caused by mesotheliosis can be treated by photodynamic therapy (PDT) or intraocular injection of ranibizumab, and there is no clear conclusion on which of the two is more effective. In our clinical work, we feel that some patients are well treated with PDT and some are sensitive to intraocular injection, however, a small number of patients need to take combined treatment. Although the incidence is low, intraocular injections have the potential to cause complications such as intraocular infections, which should be explained to the patient before treatment.