By dry weight, we mean that the patient has no sodium retention of water in the body and is living on his or her own, with no respiratory distress when lying down and stable blood pressure. Self-weight when feeling good about oneself. This is the ideal weight that is hoped to be achieved after dialysis treatment. The dry weight of patients with end-stage renal failure is clinically significant, and it is very important to set an appropriate dry weight for patients, which is the basis for dialysis ultrafiltration and a guarantee to improve the quality of life of patients. Letting patients know their dry weight and its clinical significance can enable them to control their water and diet well and prevent various complications caused by water and sodium retention. In severe cases, high levels of swelling, heart failure and respiratory failure can be life-threatening. In mild cases, it also makes the patient suffer from hypotension, vomiting and muscle cramps during dialysis, which add to the patient’s pain. Dry weight also changes sometimes. Regular dialysis, reasonable diet, and proper exercise make the condition stable, and dry weight will increase. Conversely, the weight will decrease, which should be corrected in time according to the actual situation in the clinic. At the same time, it is necessary to instruct patients to control their own weight and to control their water intake according to the length of their dialysis cycle. Weight gain between dialysis sessions should not exceed 5%. Advocate patients to update their concepts, change their past dietary habits, and eat more food with less water, especially anuric patients should be more strict with their water intake and not drink tea or beverages. Those who have urine can be based on their own urine volume, that is, the water intake is the previous day’s urine volume plus 500 ml. Changes noted at all times. How to determine the patient’s dry weight is, as far as it is concerned, assessed by the doctor according to the patient’s general condition and after several dialysis sessions. This is only an approximate figure, and whether this dry weight is particularly appropriate or not needs to be measured by the following aspects 1. symptoms; self-care of life, no respiratory distress, no nocturnal paroxysmal dyspnea, stable blood pressure, no generalized swelling, 2. stable cardiovascular system, no heart failure, no lung, stable blood pressure. No liver enlargement. No lower limb edema, no pleural effusion and ascites. Set an appropriate dry weight for the patient and achieve this standard after each dialysis session. Make the patient’s quality of life improved. Survival is prolonged and the overall level of dialysis is improved in a significant way.