There is no such thing as a clinically proven bone enlargement breakthrough drug. The drugs used in the treatment of osteoporosis are non-steroidal anti-inflammatory drugs (NSAIDs), opioid analgesics, and glucocorticoids. 1. Non-steroidal anti-inflammatory drugs (NSAIDs): Oral ibuprofen, celecoxib, rosoprofen sodium and other non-steroidal anti-inflammatory drugs can be prescribed by the doctor, which can effectively alleviate the symptoms of pain, and help to improve the patient’s quality of life. 2. Opioid analgesics: For those who are not effective in NSAID treatment, morphine and other drugs can be taken orally as prescribed by the doctor to relieve pain caused by osteophytes. 3. Glucocorticosteroids: Intra-articular injection of prednisone and other glucocorticosteroids can be administered under the operation of a doctor, which is effective in relieving pain in the short term. It is recommended that people with osteophytes should go to regular hospitals in time and take standardized treatment under the guidance of doctors, and should not blindly use medication on their own, so as to avoid delaying the condition.