Itchy throat and cough are mostly seen in acute pharyngitis, chronic tonsillitis, allergic pharyngolaryngitis, etc. If it is caused by a pathogenic bacterial infection that is sensitive to amoxicillin, you can take amoxicillin. 1. Acute pharyngitis: it may be caused by viral infection or bacterial infection, while amoxicillin can be used for upper respiratory tract infection, if it is caused by sensitive pathogenic bacteria infection, you can take amoxicillin orally. 2. Chronic tonsillitis: If it is a viral infection, there is no need to take amoxicillin. If it is a bacterial infection, you can take oral amoxicillin and other antibiotic drugs. 3. Allergic pharyngitis: is caused by allergen stimulation, do not need to eat amoxicillin, mainly oral loratadine, cetirizine and other anti-allergy drugs. Allergic to penicillin and positive penicillin skin test patients are prohibited. It is contraindicated for those who have serious rapid-onset hypersensitivity reactions (e.g., anaphylactic reactions) to other -lactam agents (e.g., cephalosporins, carbapenems, monocyclic -lactams). The most common adverse drug reactions reported abroad are diarrhea, nausea and rash. Itchy throat and cough, there may be other causes, it is recommended to go to the hospital in a timely manner, identify the causes and cooperate with the doctor to standardize the use of drugs and treatment.