Vitamins, especially B vitamins, have a preventive effect on the occurrence of constipation. Because certain vitamins can regulate the rate of acetylcholine hydrolysis and maintain normal nerve conduction, thus maintaining and strengthening the peristaltic function of the stomach and intestines and the secretion function of the digestive tract, thus promoting defecation. If vitamin B1 deficiency, the hydrolysis of acetylcholine is accelerated and nerve conduction is affected, resulting in digestive dysfunction such as slow gastrointestinal peristalsis and reduced secretion of digestive juices, which affects defecation and leads to constipation. Therefore, timely supplementation of patients with vitamin B1 deficiency and eating vitamin-rich foods can prevent constipation from occurring.