Cholestatic cirrhosis can be treated with medication, surgery, artificial liver therapy or liver transplantation under the guidance of a doctor in combination with the severity of the disease. Cholestatic cirrhosis is the fibrosis of liver cells caused by bile stasis, which eventually leads to the formation of cirrhosis. Patients can take ursodeoxycholic acid to relieve symptoms and slow down the progress of the disease. In addition, immunosuppressants such as methotrexate can be used for treatment. Cirrhosis caused by bile duct stenosis can be treated by surgically placing a biliary stent to treat the disease. If the cirrhosis becomes decompensated, artificial liver treatment can be chosen to improve the symptoms under the doctor’s evaluation, and if necessary, liver transplantation can be accepted to treat the disease. Therefore, it is recommended that patients actively cooperate with doctors to receive standardized treatment and follow the doctor’s instructions to use medication, which can significantly control the progression of the disease and improve the prognosis of the disease.