Leukemia is a malignant neoplastic disease of the hematopoietic system. At present, there is no clinical rule which 6 kinds of fruits cannot be eaten by leukemia patients, and patients can choose according to their own situation and doctor’s advice. However, when consuming fruits, some matters should be noted to avoid causing discomfort. Before eating fruits, leukemia patients must wash them and peel them before eating them. If it is not convenient to chew directly, it can be cut into small pieces or squeezed into juice. If the fruit shows mold or insect eyes, it should not be eaten and should be discarded immediately. Avoid allergic or intolerant fruits, as well as fruits that are too cool or too hot in nature, commonly too cool fruits such as watermelon, apple, banana, etc., and too hot fruits such as jujube, hawthorn, etc. The amount of fruit eaten each time should be moderate to avoid diarrhea. In addition, because some ingredients contained in grapefruit fruits can inhibit the effect of targeted drugs, such as grapefruit, thus patients should avoid eating them as much as possible to avoid affecting the efficacy of the drugs. In addition, patients with a weak spleen and stomach during radiation therapy or chemotherapy can eat fruits that are easy to digest and have a soft taste, such as peach, etc. Avoid fruits that have just been taken out of the refrigerator and fruits with high protein and sugar, which may be indigestible and cause discomfort. At the same time, patients can eat fruits that are rich in iron and vitamin C, such as cherries, raisins and kiwifruit. In daily life, leukemia patients should have a reasonable diet, supplement nutrition, choose easily digestible and harmless foods, and avoid fried foods and foods that are too hard, such as fried chicken. When eating fish, try to remove the bones and spines first or choose fish without spines to avoid damaging the oral mucosa causing mouth ulcers and even secondary oral infections and other undesirable conditions.