Condyloma acuminatum is a common sexually transmitted disease caused by human papillomavirus (HPV) infection, which mainly manifests as proliferative lesions on the skin and mucous membranes. There are different subtypes of HPV. The most common types of HPV that cause warts are 6, 11, etc. HPV is easy to survive and reproduce in warm and humid conditions, so the external genitalia and the perianal area are the most susceptible sites for infection. In recent years, the incidence of condyloma acuminata has been on the rise, ranking as the second most common sexually transmitted disease in China. The actual fact is that you can find a lot of people who have been trying to find a solution to the problem of recurrence of warts.
The actual fact is that you can find a lot of people who are not able to get the best out of your own home.
1, sexual contact transmission is the most important way of transmission. The actual fact is that the actual people who have been in a sexual relationship are prone to it.
The actual fact is that you can find a lot of people who have been in contact with the patient’s items, such as underwear, underwear, towels, bath tubs, toilet rings, etc.
3.Mother-to-child transmission of laryngeal papillomatosis in infants through the birth canal during childbirth.
Topical drug treatment
1.Cytotoxic agents.
Mainly through the anti-proliferation or chemical corrosion effect works.
(1) 10%-25% tincture of ampicillin of pediculosis (ghost resin). Disadvantages: If the drug is not used carefully or not make it dry, the liquid spills nearby parts, can lead to local redness, vesicles and ulcers, etc., serious cases can occur necrotizing glansitis, vulvar skin necrosis, etc.. It is prohibited for pregnant women.
(2) 5-FU cream. The local inflammatory irritation response is small, painful ulcers are common adverse reactions, but does not cause local tissue necrosis. Disadvantages: acromegaly is prone to recurrence, has teratogenic effects, and is prohibited for pregnant women.
(3) Trichloroacetic acid. It is a good idea to use it as a treatment for warts. The disadvantage: easy to damage the adjacent normal tissue, local may have stinging, erosion, ulceration, epidermal scarring, secondary infection and other adverse reactions.
(4) 5% dunzamonium bromide solution. The cationic surfactant, can make the vacuolated condyloma acuminata tissue cytoplasmic components exuded and make the warts atrophy off, almost no harm to normal tissue. It is also useful for the treatment of subclinical and latent infections. The disadvantage: high recurrence rate.
2, local immunomodulators.
(1) Imiquimod. It is a topical immune enhancer. There are local reactions of varying severity such as erythema, edema and erosion, and local pigment loss in a few patients. Use with caution in pregnant women. It is suitable for smaller warts and can prevent recurrence of warts. Disadvantages: there is a certain recurrence rate. The effect is worse for larger warts.
(2) Interferon gel. The actual fact is that it is a good deal more than just a few of the most popular and also the most popular. Disadvantages: the role of limited, high recurrence rate.
3, Chinese medicine preparations.
Warts net, remove warts net, Paitling, etc. Disadvantages: local superficial erosion, burning pain is obvious. There is a certain corrosive and recurrence rate.
4, physical therapy.
Electrical cautery, cryotherapy, microwave therapy, laser therapy and radionuclide therapy.
(1) Freezing: freezing leads to local edema and erosion, longer recovery time, blister breakage and erosion, longer healing time, so it can lead to local skin virus reinfection, which may be the main reason for the poor effect of freezing treatment and recurrence.
(2) electric cautery, microwave therapy, laser treatment lesion recovery speed is faster than freezing healing, and lesions are relatively dry, so the recurrence rate is relatively freezing small.
The actual fact is that you can find a lot of people who are not able to get a good deal on a lot of things. The relative recurrence rate is much smaller.
5, photodynamic (5-ALA-PDT) treatment. Advantages: no damage to normal mucosal tissue, no ulcers and scar formation. Low recurrence rate and good tolerability. Disadvantages: the treatment process has a certain stinging pain, high cost.
6, surgical treatment. Mainly for the large warts.
7, Chinese herbal medicine therapy. The Chinese medicine oral and Chinese medicine fumigation, the latent infection and subclinical infection effect is sure.
8, immunotherapy. The main drugs are interferon, BCG polysaccharide nucleic acid, 5-Fu, interleukin, levamisole, polymyxin, thymidine, human placental lipopolysaccharide and mannan peptide. It has some effect in adjuvant therapy.
9, artificial immunotherapy. That is, autologous wart inoculation, because of the risk of causing secondary infection and other infections, there is no promotion of this treatment method.
In conclusion: according to the patient’s medical history, the size of the lesions, number, location, morphological characteristics, patient compliance, choose the right combination of therapy is the best choice for the prevention and treatment of condyloma acuminata.