The absolute value of monocytes is 0.05 higher, physiological can be seen in infants and children, and pathologic can be seen in certain infections, hematological diseases and so on. 1. Physiologic: can be seen in infants and children. 2. Pathologic (1) Infection can be seen in infective endocarditis, active tuberculosis, etc., mainly using anti-infective drugs such as penicillin; anti-tuberculosis drugs such as rifampicin, isoniazid, streptomycin and ethambutol. (2) Blood diseases can be seen in chronic granulocytic leukemia, myelodysplastic syndromes, etc. The drugs hydroxyurea, interferon, thalidomide, or hematopoietic stem cell transplantation can be used. The examination found mononucleosis should actively seek medical treatment to clarify the causes of mononucleosis, and targeted treatment under the guidance of professional doctors to maximize the quality of life.