In recent years, with the rapid development of orthopedic technology, the number of surgeries has increased, the demand for blood has gradually increased, and the phenomenon of blood shortage has been highlighted, while the large amount of blood lost during surgery is not recycled and utilized, which also results in a waste of blood resources. The two major problems facing blood transfusion are the occurrence of blood-borne diseases that may be caused by allogeneic blood transfusion, and the shortage of blood source and the complications of blood transfusion. Therefore, autologous blood recovery has been increasingly emphasized and widely adopted at home and abroad. Reducing intraoperative blood transfusion and preventing transfusion reactions have always been our concern. In accordance with the requirements of the review of the third-class hospital and the deployment of the hospital, on the basis of the autologous blood transfusion last year, our department has recently carried out a variety of transfusion techniques, including preoperative autologous blood collection for complex orthopedic spine surgery, acute isovolumic dilution, intraoperative blood pressure control, and intraoperative autologous blood transfusion with the help of preoperative accurate assessment, communication with the blood bank, and assistance from the department of surgical anesthesiology. The clinical application of various blood transfusion techniques for complex orthopedic surgical blood transfusion has made useful exploration and accumulated experience. It has been proved by clinical practice that it is safe and reliable, can significantly reduce the amount of blood transfusion, has no obvious effect on blood components, and has clinical application value. It is safe, economical and feasible, and can significantly reduce or avoid allogeneic blood transfusion. Thus, the risk of allogeneic blood transfusion is reduced or avoided, the tension of blood supply is alleviated, and more importantly, the medical safety of both doctors and patients is increased and the occurrence of medical errors is reduced.