Condyloma acuminatum is a sexually transmitted disease caused by human papillomavirus (HPV) infection with proliferative damage to the anogenital area. It occurs mostly in young and middle-aged people between the ages of 18 and 50. The disease develops after an incubation period of about half a month to 8 months, with an average of 3 months. The disease is more common and is transmitted mainly through sexual contact. The HPV infection of the host can have the following three manifestations 1, condyloma acuminata; 2, subclinical infection: usually refers to clinically unrecognizable lesions, but with 3-5% acetic acid solution locally applied externally or wet compresses for about 5min, can be seen in the HPV infection area uniform whitening, the so-called “white acetate test” positive; 3, latent ( 3, latent (occult) infection: negative white acetate test, but the skin lesion biopsy with antigen or nucleic acid test shows the presence of HPV infection. （The incubation period: 1 to 8 months, usually 3 months. （The first of these is the first of a series of new products that are available in the market. The lesions may vary in shape and size depending on the period or location of growth. Initially, multiple pink, gray-white or gray-brown papules appear locally, gradually developing into papillae, corns, cauliflower or masses of superfluous lesions. In a few patients, the lesions become hyperplastic and become giant condyloma acuminata, also known as Buschke-L?wenstein giant condyloma acuminata, which is mainly seen in people with HPV-6 infection, the histology of which is mostly benign, but a few can be malignant. Patients may feel itching, foreign body sensation, pressure or burning pain, often bleeding or secondary infection due to increased fragility of the lesions. Women may have increased vaginal discharge. However, about 70% of patients do not have any conscious symptoms. (d) White acetate test Apply 3-5% acetic acid solution to the lesion to be examined and the surrounding skin mucosa, and within 3-5 min, if a uniform white area is seen, it may be HPV infection. It is easier to observe if used in conjunction with a magnifying glass or colposcope. This method is simple and practical, but false positives can occur when there is local inflammation. The difference is that a positive white acetate is a uniform white area with slightly elevated edges and clear borders, whereas a false positive is an uneven white with blurred borders, the latter mostly seen in non-specific vulvodynia or glans penis. The mechanism of this method is not fully understood, and it may be that the infected epithelial cells have increased expression of keratin in the epithelium, which is susceptible to whitening by acetic acid coagulation. However, white acetate is not a specific test for HPV infection, and the specificity and sensitivity of screening with this method is unclear. The routine use of the white acetate test to detect “subclinical” genital warts is not recommended. However, some experienced clinicians have used this test to identify flat genital warts.