Sorbitol, also known as sorbitol, is a sweetener with a certain sugar content, which will raise blood sugar if consumed in excess, but if consumed normally will not lead to a rise in blood sugar. After entering the body, sorbitol can be transformed into fructose by the action of sorbitol dehydrogenase, and enter the process of glycolysis through a series of complex changes. Fructose metabolism in the body is not controlled by insulin, in the process of transformation will not cause a rapid rise in blood sugar, so sorbitol to become glucose also needs to go through fructose-1-phosphate and then decompose into propanose, propanose further synthesis of glucose and triglycerides, and enter the pathway of glycolysis. Because the decomposition steps are more, so the effect on blood sugar is not very big, usually add sorbitol as sweetener in food. For diabetic patients, patients with abnormal glucose tolerance, and patients with impaired fasting blood sugar, it is not recommended to eat sorbitol in large quantities, and it can be consumed in moderation. Although sorbitol does not raise blood sugar very significantly, sorbitol, if excessive, can easily lead to the development of microangiopathy.