In the past, most of the complicated kidney stones were treated by open surgery, but it has the disadvantages of large surgical trauma, slow postoperative recovery and residual stones. Percutaneous nephrolithotripsy is a new technology developed in recent years, and its advantages are becoming more and more obvious with the continuous improvement of instruments and technology. Percutaneous nephrolithotomy with ultrasonic lithotripsy or pneumatic ballistic lithotripsy is an effective means of treating complex kidney stones, but both have advantages and disadvantages. Although ultrasonic lithotripsy has the function of crushing and removing stones, its lithotripsy efficiency is low, especially for the large hard stones, pneumatic ballistic lithotripsy improves the lithotripsy efficiency, which can quickly crush the stones in a relatively short period of time, but it can’t remove the stones, which increases the operation time, intraoperative and postoperative time. However, it cannot remove the stones, which increases the operation time and the incidence of intraoperative and postoperative complications. Cyberwand is not only a very efficient lithotripter, but also simple to set up and easy to operate, Cyberwand dual catheter ultrasonic lithotripsy system uses a single ultrasound energy source, utilizes the patented free vibrator technology to perfect the combination of high-frequency ultrasonic vibration and low-frequency impact, with high efficiency of lithotripsy, large space for stone evacuation and simple operation, which makes up for the insufficiency of ultrasonic lithotripsy and pneumatic ballistic lithotripsy, and thus improves the efficiency for various hardness and complexity of lithotripsy. It improves the lithotripsy and stone removal effect for complex stones of various hardness. The ultrasonic energy generated by Cyberwand has a strong effect on stones and is ineffective against tissues, which avoids the damage of catheter to tissues. The active negative pressure suction device keeps the renal collecting system in a low-pressure state, which reduces the chance of infection caused by bacteria entering the bloodstream, and also reduces the damage to renal function caused by the flushing fluid in a high-pressure state. The ultrasonic adsorption function can also suction out the small stones hidden in the renal calyx, which significantly improves the stone removal rate and reduces the residual stones after operation. Ultrasound-guided percutaneous nephrolithotripsy is an important part of endoluminal urological surgery. Ultrasound can not only provide information about the internal structure of the punctured kidney, the relationship between the stone and the calyx, the thickness of the renal cortex, and the structures through which the puncture route passes, but also monitor the direction of the puncture needle penetration during the operation, so that it is not easy for the puncture route of the puncture site to be shifted. Ultrasound was applied to guide the establishment of the skin renal channel, which allowed clear observation of the stone and the calyx in the area where the stone was located, and the guidewire was placed after successful puncture to guide the dilator to dilate the channel to F24. Since the size of the surgical channel did not have a statistically significant effect on the damage to the renal cortex, a large channel could increase the speed of intraoperative stone discharge, reduce the duration of the procedure and the chance of reoperation, as well as reduce the intrarenal perfusion pressure. The application of percutaneous nephrolithotripsy with Cyberwand dual catheter ultrasonic lithotripsy system for the treatment of complex renal stones has the advantages of high efficiency, reliability, safety, less injury, less bleeding, and faster recovery, which is worthy of clinical promotion.