There is individual variability in that some patients will lose weight with simethicone. 1. Simeglutide is a glucagon-like peptide-1 receptor (GLP-1) agonist, which can enhance insulin sensitivity, slow gastric emptying, act on the hypothalamus to inhibit appetite, reduce body weight, and through these effects together to achieve the effect of lowering sugar. 2. The most common adverse reactions to simethicone are digestive symptoms such as nausea and diarrhea. Some people may have no specific reaction. Its weight loss effect also varies from person to person. Do not use the drug blindly, and seek medical advice immediately if any uncomfortable symptoms occur. It is recommended to use the drug correctly under the guidance of a professional doctor, do not use it privately.