Rheumatoid is a chronic disease that generally cannot be completely cured. It is easy to have recurrent attacks, although not completely cured, but early and effective treatment can still control the disease, the medication time is relatively long. Do not be too anxious, usually need to pay attention not to strain and cold, keep a relaxed mood, etc. ….. 1, non-steroidal anti-inflammatory drugs? There are anti-inflammatory and pain relief, reduce stiffness and muscle spasm. Such as ibuprofen, diclofenac sodium tablets, clonoxicam, ciloxib, etc. The side effects are gastrointestinal reactions, kidney damage, prolonged bleeding time, etc. Special attention should be paid to pregnant and lactating women. 2.Methotrexate: side effects include gastrointestinal reactions, bone marrow suppression, stomatitis, hair loss, etc. Check liver function and blood picture regularly during the medication period, and avoid drinking alcohol. 3, hormones: such as prednisone, in general, without adrenocorticotropic hormone therapy RF. 4, tretinoin: the initial domestic use of tretinoin. Have anti-inflammatory and analgesic effect, the efficacy is better than the tincture, easy to take. Side effects are gastrointestinal reactions, leukopenia, menstrual disorders and reduced sperm vitality, etc., can be restored after discontinuation of the drug. 5, biological agents: tumor necrosis factor (TNF-α) antagonists (such as class grams, Yicep, adalimumab, etc.) is currently the best choice for the treatment of RF spinal joint disease, those who have the conditions should try to choose rheumatoid arthritis can not be cured, there will be some discomfort when the climate change or change of season, is a normal reaction, do not stress. Most of the mild symptoms will be relieved in a stable climate or after the change of seasons, if not relieved by itself, then take medication to treat.